#Name Ontology File Suffix Result File Description Link LinkName biological process biological_process.genes biological_process.txt Functional groupings of proteins http://www.geneontology.org Gene Ontology molecular function molecular_function.genes molecular_function.txt Mechanistic actions of proteins http://www.geneontology.org Gene Ontology cellular component cellular_component.genes cellular_component.txt Protein localization http://www.geneontology.org Gene Ontology chromosome location chromosome.genes chromosome.txt Genes with similar chromosome localization http://www.ncbi.nlm.nih.gov/gene NCBI Gene KEGG pathways KEGG.biosystems.genes kegg.txt Groups of proteins in the same pathways http://www.genome.jp/kegg/pathway.html KEGG protein interactions interactions.genes interactions.txt "Proteins interacting with a common protein (BIND, EcoCyc, HPRD)" http://www.ncbi.nlm.nih.gov/gene NCBI Gene interpro domains interpro.genes interpro.txt Proteins with similar domains and features http://www.ebi.ac.uk/interpro/ Interpro pfam domains pfam.genes pfam.txt Proteins with similar domains and features http://www.sanger.ac.uk/Software/Pfam/ Pfam smart domains smart.genes smart.txt Proteins with similar domains and features http://smart.embl-heidelberg.de/ SMART gene3d domains gene3d.genes gene3d.txt Proteins with similar domains and features http://cathwww.biochem.ucl.ac.uk:8080/Gene3D Gene3D prosite domains prosite.genes prosite.txt Proteins with similar domains and features http://ca.expasy.org/prosite/ Prosite prints domains prints.genes prints.txt Proteins with similar domains and features http://www.bioinf.manchester.ac.uk/dbbrowser/PRINTS/ PRINTS MSigDB lists msigdb.genes msigdb.txt "Genes sets for pathways, factor/miRNA target predictions, expression patterns, etc." http://www.broadinstitute.org/gsea/msigdb/index.jsp MSigDB BIOCYC pathways BIOCYC.biosystems.genes biocyc.txt Groups of proteins in the same pathways http://biocyc.org/ BIOCYC COSMIC cancer mutations cosmic.genes cosmic.txt Genes mutated in similar cancers http://cancer.sanger.ac.uk/cancergenome/projects/cosmic/ COSMIC GWAS genes gwas.genes gwas.txt Genes mutated in similar diseases http://www.genome.gov/26525384 GWAS Catalog Lipid Maps pathways LIPID_MAPS.biosystems.genes lipidmaps.txt Groups of proteins in the same lipid pathways http://www.ncbi.nlm.nih.gov/biosystems/ Lipid Maps/Biosystems Pathway Interaction DB Pathway_Interaction_Database.biosystems.genes pathwayInteractionDB.txt Groups of proteins in the same pathways http://pid.nci.nih.gov/ Pathway Interaction Database REACTOME pathways REACTOME.biosystems.genes reactome.txt Groups of proteins in the same pathways http://www.reactome.org/PathwayBrowser/ REACTOME SMPDB pathways smpdb.genes smpdb.txt Groups of proteins in the same pathways http://www.smpdb.ca/ SMPDB WikiPathways WikiPathways.biosystems.genes wikipathways.txt Groups of proteins in the same pathways http://www.wikipathways.org/index.php/Special:BrowsePathwaysPage Wikipathways